Novel Method for Radiolabeling and Dimerizing Thiolated Peptides Using 18F-Hexafluorobenzene
نویسندگان
چکیده
منابع مشابه
A novel method of 18F radiolabeling for PET.
UNLABELLED Small biomolecules are typically radiolabeled with (18)F by binding it to a carbon atom, a process that usually is designed uniquely for each new molecule and requires several steps and hours to produce. We report a facile method wherein (18)F is first attached to aluminum as Al(18)F, which is then bound to a chelate attached to a peptide, forming a stable Al(18)F-chelate-peptide com...
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ژورنال
عنوان ژورنال: Bioconjugate Chemistry
سال: 2015
ISSN: 1043-1802,1520-4812
DOI: 10.1021/acs.bioconjchem.5b00278